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4/18/2023 0 Comments Rar for mac osxYou can use this tool for managing a variety of archives like ZIP, TAR, GZIP, etc. Easy Way to Open RAR Archivesĭespite the fact that macOS and OS X provide a built-in archive utility tool, it is not capable of opening RAR files. And, if you haven’t noticed yet, “.rar” is the extension of these files (example tutorials.rar). So, RARs are undeniably high-quality archiving formats, which you will meet frequently. RAR archives use secure AES-128 encryption standard and offer higher compression ratios compared to the ZIP files. If you are asking, why people use RAR instead of ZIP files, I would say, because it is more efficient in every aspect. You must install third-party software to access extract RAR archives. However, macOS does not have native support for RAR files. Mac operating systems provide a built-in ZIP extractor. However, this procedure is mandatory for all archive file formats like ZIP, RAR, 7-zip, TAR, etc. The only downside of using RAR files is that you must unpack the archive before you access the compressed content. These RAR archives are ideal for sending a variety of files via emails or other sharing methods. The final compressed archive file is much smaller compared to the size of the uncompressed files and folders included in it. People use these RAR files for decreasing the overall size and packing together various files and folders into a single file. They are widely used for sharing and transferring data through the internet. Roshal Archive Compressed (RAR) files are one of the most popular archive file formats for compressing data. In this article, we will show you an easy way to extract RAR files on MAC OSX. However, because macOS does not include a native RAR explorer, it can be a little tricky. If you like to view and use the compressed data on your Mac, first, you need to extract the RAR file. Are you familiar with RAR files? Majority of the file content that you download from the internet comes in compressed. The Freedom Chevrolet service and parts facility has a full inventory of authentic parts as well as the necessary tools to address most automotive questions and issues. Worst Service department ever I make a reservation to get my Corvette serviced I get to the service department and they say they dont have that item. Search for other New Car Dealers in San Antonio on The Real Yellow Pages®. Freedom Chevrolet offers a service and parts department near San Antonio, where you'll receive attentive customer service and timely completion of work done on your vehicle. Search for other New Car Dealers in San Antonio on The Real Yellow Pages®. It additionally offers various leasing programs and financing options. Get reviews, hours, directions, coupons and more for Vara Chevrolet at 8011 Interstate 35 S, San Antonio, TX 78224. Freedom Chevrolet Chevrolet Dealer San Antonio Tx Fill up our online service appointment form to schedule an auto service. That has proved to be an incorrect assumption and I am disappointed and seriously inconvenienced, and I will take both my business and my vehicle ownership elsewhere in the future. The dealership has a service center that provides lube, oil and filter changing services. (Photo courtesy of the Pomona Police Department) The crew contacted Union Pacific Railroad. I trusted that their dealerships would know how to handle this new technology and the service/repairs that are required. BNSF Railroad Police Officer Seen in San Bernardino, California. I purchased a Volt with the understanding that GM was on the forefront of new and efficient technology for vehicles. I caution anyone seeking service for their electric or hybrid electric vehicle against using this dealership for their Chevy. Freedom Chevrolet San Antonio - Chevrolet, Service Center - Dealership Ratings Freedom Chevrolet San Antonio 13483 I-10 West, San Antonio, Texas 78260 Directions Sales: (210) 697-6070 2.0 101 Reviews Write a Review Nearby Certified Dealers Don Ringler Chevrolet 4.8 783 Lifetime Reviews Read Reviews Capitol Chevrolet 4. I took my car to this dealership hoping for better service than at the last Chevy dealership, Northside Chevrolet, and Freedom was was doing well until this situation. This is incorrect as I discovered later that my car is not being repaired, nor are parts being ordered (which is what I was told by Vanderpot), but instead my car is sitting in their holding lot. Instead I was brushed off by the young woman who took my call, telling me that, “she was unable to see any details only that my car was ‘being repaired’”. I have not gotten updates nor was I given an update when I called. Even after all of that, and getting the approval for my vehicle’s repair, and being notified by the warranty company that the repair has been approved, my car is still waiting to be serviced. Although at first Justin Vanderpot was helpful, I ended having to call my warranty company myself and gather all the paperwork for my repair approval. After seven weeks, my 2017 Chevy Volt is still waiting to be serviced and repaired. I cannot recommend this dealership for service. In other words, it requires a constant exploration and willingness to reinvent what it means to be vegan. Questions that come up while playing characterize the vegan movement at large and include things like ‘what is considered a living creature?’, ‘when is hurting another creature as a form of self-defense appropriate?’, ‘what should I do if I receive an item that contains animal products as a gift?’. So instead of a predefined set-out challenge (such as “don’t kill anyone” (in the case of pacifist-runs) or “complete the game as fast as possible” (in the case of speed-runs)) the game is approached according to values that can be negotiated with. Veganism is understood here as a general and interpretable ideology, not a strict set of rules. Similar to speed-runs or pacifist-runs, but with a clear focus on improvised decision making that is based on a guiding set of broadly interpretable values. This type of adjusted playing style is also called ‘ expansive gameplay‘. ( BOTW) (Nintendo, 2017) through a vegan-run I tried to practice Foucauldian self-fashioning with my-self (both virtual and actual) through disruption and destabilization of the default gameplay. This is done by taking the liberty to impose rules and disciplines over our own lives that shape specific ways of living freely within existing structures of domination and oppression.īy playing The Legend of Zelda – Breath of the Wild. In this context, self-fashioning refers to the constant and life-long practice of exerting power over one’s own life in order to find a personal sense of freedom. He hoped that freedom could be obtained through the practice of ‘care for the self’: to give a certain shape or style to one’s own life as a form of ethical or aesthetical self-fashioning (Foucault, 1988). The methods and practices that could be used for styling or transforming one’s self were defined by Foucault as ‘ technologies of the self’ (Foucault, 1988, p. He aimed to reframe our understanding of concepts like power and freedom not as static limitations but as arbitrary constraints that can be negotiated with and that give us the possibility to continuously reshape ourselves. Particularly in his later work, he emphasized the active and critical negotiation we can have with power structures as well as practicing different ways of living with limitations. Michel Foucault (1926-1984) was a French philosopher that focused his work on notions of power, freedom, and knowledge. On the other hand, I eat a lot of veggies and I do my best to fight the evil spirit of Ganon.” I don’t kill or bully other creatures, I don’t buy any leather or wool clothing items, I don’t pick up weapons made of bones, and I don’t tame or ride horses. In fact, I try to avoid all aspects of speciesism that I encounter during my adventures. This does not only mean that I refuse to eat animal products. This is because I am the chosen one who explores the virtual world of the Zelda game series as a protagonist, while pursuing an important quest for justice and peace. I tried to leave out as much academic jargon and complexity as possible, while keeping the main points of the text. (In this post I summarize a research paper I recently presented at the Philosophy of Computer Games conference. It includes the classic Sling Scope and Super Seeds, but with 1 new powerup, called the Homing Bird, is Red Bird wearing a robotic hat and has a radar that surrounds him, and he is able to destroy more of the structure. ANGRY BIRDS SEASONS 23 UPDATEĪlso there is another new powerup, that came in the Abra-ca-Bacon update (v 3.3.0, ), called Allaka-BAM, are similar to the TNT Drop powerup from Angry Birds Rio, but more powerful. The Allaka-BAM items are a box with a star on it when dropped are black, and then shortly turn blue. When a bird or block hits it, it will explode with magic. Like Angry Birds, Angry Birds Seasons has golden eggs. There are at least 1 or 2 hidden in the levels, except for Easter Eggs which has 10 in PC and Mac and 11 on every other device, and Mooncake Festival has Golden Mooncakes, which are similar to Golden Eggs. If you collected all the golden mooncakes, you have a bonus level. Also, like the original game, Angry Birds Seasons gives you a bonus level to get three stars on all levels (which is incredibly hard). Here is the list of all the episodes in Seasons 1 (or Seasons 2011). All of the first seven birds (Red, Blue, Yellow, Black, White, Green, and Big Brother) appear in all episodes.ġ. Trick or Treat:Halloween 2010, October 21st 2010Ģ. Season's Greedings:Christmas 2010, December 1st 2010ģ. Moon Festival:Moon Cake Festival Celebration 2011, September 1st 2011 Hogs and Kisses:Valentine's Day 2011, February 7th 2011Ĥ. Here is a list of all the episodes in Seasons 2 (or Seasons 2012). All of the first seven birds appear, but two new birds (Orange in Ham'o'ween, Pink Bird in Back to School) appear in the season. In the Year of the Dragon episode, the Mighty Dragon replaces the Mighty Eagle.Ĩ. Wreck the Halls:Christmas 2011, December 1st 2011ġ0. Year of the Dragon:Chinese New Year 2012, January 19th 2012ġ1. (Image credit: BBC) June 2022 Netflix Premieresįans of the acclaimed crime drama series Peaky Blinders will have reason to celebrate in June 2022 as the show's sixth season is set to debut.Cherry Blossom:Japanese Cherry Blossom Festival 2012, March 8th 2012ġ2. Pokémon Master Journeys: The Series: Part 3 GHOST IN THE SHELL: SAC_2045 SUSTAINABLE WAR Netflix subscribers will be able to go back to Hawkins, Indiana, in May 2022 when the first half of Stranger Things Season 4 makes its debut. (Image credit: Netflix) May 2022 Netflix Premieres Grace and Frankie Season 7 Ozark Season 4 Part 2 GREEN MOTHERS' CLUB JIMMY SAVILE: A BRITISH HORROR STORY THE ULTIMATUM: MARRY OR MOVE ON Not a whole lot has been announced for Netflix's April 2022 offerings, but we will see the return of Ultraman. (Image credit: Netflix) April 2022 Netflix Premieres HEI$T: THE GREAT ROBBERY OF BRAZIL'S CENTRAL BANK The Parisian Agency: Exclusive Properties Season 2Īn Astrological Guide for Broken Hearts Season 2 He-Man and the Masters of the Universe Season 2 You can also expect to see some engaging true crime documentary series, which seems to have become the bread and butter of Netflix's non-fiction offerings as of late. The third month of 2022 will see the long-awaited premiere of Bridgerton's second season. (Image credit: Netflix) March 2022 Netflix Premieres Expect to hear more about the slate of February Netflix TV show premiere dates in the near future.įORECASTING LOVE AND WEATHER TWENTY FIVE TWENTY ONE The second month of 2022 will debut of Love is Blind: Japan as well as the return of Sweet Magnolias for a second season. (Image credit: Netflix) February 2022 Netflix Premieres THE WOMAN IN THE HOUSE ACROSS THE STREET FROM THE GIRL IN THE WINDOW Pokémon Master Journeys: The Series Season 2 The first month of the year will also see the debut of Getting Curious with Jonathan Van Ness, the streaming adaptation of the Queer Eye host’s popular podcast. Netflix isn’t wasting any time with its offering of original series in January 2022, especially with the long-awaited debut of the first set of episodes from Ozark Season 4 (the second half will follow later in the year). (Image credit: Netflix) January 2022 Netflix Premieres GUILLERMO DEL TORO’S CABINET OF CURIOSITIES THE TRAPPED 13: HOW WE SURVIVED THE THAI CAVE Each object can have many types of animations, such as rotate, rotate, beat, wave, blur, typewriter, pulse. 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Using just a single timeline, you’ll be able to control all aspects of your animation, including its length, speed of playback, and much more! Or apply motion effects like Linear, Quad, Cubic, and Quit to add choreography like bounce and twists. Imagine applying particle effects to simulate fireworks, smoke, snow, flame, or the emptiness of space. Download Aurora 3D Animation Maker 20 + Portable Aurora 3D Animation Maker 20Įasy 3D Animation Software | Movie Title Animation CreatorĪurora 3D Animation Maker creates limitless special animation effects, as far as your creativity can go, to further liven up your creations. 4/17/2023 0 Comments Autumn reeserMethodically teaching myself for years how to cook, and then going ‘off-roading’ from recipes. You’re proud of this accomplishment, but why? My sister’s book blog, The Instant Librarian. Wil Wheaton, Patrick Stewart, and Jonathan Frakes were all the early formidable crushes of my girlhood. I relate to Nora’s transformation in Henrik Ibsen’s A Doll’s House and I also relate to both sisters’ journeys in John Madden’s film, Proof. The latest book or movie that made you cry?ĭoes YouTube’s “Double Rainbow” count? Otherwise it would be Michael Chabon’s novel, The Adventures of Kavalier and Clay.Ģ. She swings by PopMatters 20 Questions to discuss, among other things, an impulsive tendency to organize closets in her spare time.ġ. Recently, she was on the big screen in the prequel Smokin Aces 2: Assassins Ball and MTV’s made-for-TV musical The American Mall, she’s starred in the horror film Lost Boys 2: The Tribe, and wrapped production on the independent film Possessions and on The Big Bang opposite of Antonio Banderas, to name but a few of her projects. The UCLA theatre major was clearly destined for an acting career. agent Lizzie Grant in Entourage, and as the lab assistant, ‘Katie’, in No Ordinary Family opposite Michael Chiklis and Julie Benz.Īlthough Cinderella inspired her to get into theatre at a very young age, it was on Star Trek: Voyager where she landed her first paying gig. This season we’re catching a lot of her on the small screen, both as Jr. You probably know Autumn Reeser best as the teen queen ‘Taylor Townsend’ in the final two seasons of The OC. 4/17/2023 0 Comments Kids review sherlock holmes 2009Lin's invocation of yin and yang calls out another interesting dimension in the new Holmes franchise: Its embrace of action choreography, visuals and even humor that have, well, a distinctively Asian flavor.įor example, Holmes is presented as an expert martial artist - and not in the quintessentially English "sweet science" of boxing, but in a distinctively Asian-inspired discipline, full of chops, kicks, throws and holds that wouldn't be out of place in a dojo or octagon. That's a classic setup for any generation - yin meets yang." "Holmes and Watson, Riggs and Murtaugh, Butch Cassidy and the Sundance Kid. "The thing we saw was that the original stories were really classic buddy-cop adventures that happened to be told in a period setting," says Lin. The reinvention of Holmes offers a fascinating example of how that could happen. How can we take these stories and do them in a better way today?" Instead of suppressing it, you have to come to terms with it. I think we need an honest reckoning with America's racist past, which is also very rich with creativity. "Anyone who wants to bring him back hits that taboo. "There's just one reason why Charlie Chan is still dead today, and that's the history of yellowface," says Yunte Huang, whose book " Charlie Chan: The Untold Story of the Honorable Detective" is a fascinating investigation into the history and real-life inspiration behind Earl Derr Biggers's character. The forces that have stopped prior attempts to reclaim this piece of Hollywood history aren't economic, but political. So there's no commercial reason to believe that Chan couldn't make a comeback, given the right cast, director and revisionist reboot. (According to New Yorker writer Jill Lepore, they were the primary engine keeping 20th Century Fox alive during the Great Depression.) Though Chan faded from the spotlight in the '50s, two decades later, he was revived in the oddest of contexts: An animated Hanna-Barbera kids' series called " The Amazing Chan and the Chan Clan," featuring a cartoon version of the detective and his ten crime-solving kids, which ran for two seasons on CBS in the early '70s, and can still be seen in reruns today on the cable channel Boomerang. The first Holmes film made half a billion dollars worldwide.Īnd believe it or not, Charlie Chan's track record in Hollywood stands toe-to-toe with that of his British counterpart: Most of the 46 movies made in the '30s and '40s featuring the mild-mannered Hawaiian detective were huge box office successes. "People didn't think it would play with contemporary audiences." Until, of course, they found out otherwise. "We were pitching a period action film with actors speaking in British accents," says Lin. He's a known quantity.īut Dan Lin, producer of the new Sherlock Holmes franchise, says that his idea to do a new take on the chronicles of 221-B Baker Street's celebrated tenant initially met with broad skepticism. Hollywood has produced dozens of film and television adaptations of Arthur Conan Doyle's tales. You might think the comparison is laughable Sherlock Holmes is a classic character, rooted in stories that stood the test of generations. The reason I bring this up is because it actually raises an interesting question: If Sherlock Holmes can be resurrected and refreshed for a brand new generation…why not Charlie Chan? Now, to be clear, I don't think the passing yellowface moment in "A Game of Shadows" is particularly offensive there's a context for it in the plot, and even if it's played for laughs, well, so are all of Holmes's fanciful disguises. Because the most famous Asian gumshoe in the grand canon of Hollywood cinema is also the one most famously played by non-Asian actors: Charlie Chan, the rotund spouter of fortune-cookie wisdom portrayed onscreen in forty-odd feature films by the likes of Warner Oland, Sidney Toler and Roland Winters, all of them white guys wearing makeup very similar to Downey's "Chinaman" outfit. 4/17/2023 0 Comments Bryce hirschberg dillon passageJeff Duncan, who manages Francesca Farago, Harry Jowsey, & Dillon Passage, shared a post a few days back clicking the cross-collaboration between the three shows. The single contestants have to stay on an island, interact, and take part in raunchy activities with one another without being allowed sexual contact of any kind to help them build deeper emotional connections.ĪLSO READ| 'Tiger King' Bags 6 Emmy Nominations, Including 'Outstanding Documentary Series' Too Hot To Handle stars clicked with Tiger King & Love is Blind cast It features Chloe Veitch, Rhonda Paul, Haley Cureton, Madison Wyborny, Nicole O'Brien, and others. Too Hot to Handle is another dating show with a unique concept described as “meeting and mingling in Paradise”. Contestants have to go on dates and fall in love with one another without being allowed to see each other in person until one of them proposes. It is a 2020 reality show that can be binged watched on Netflix. Love is Blind is a reality dating show hosted by Vanessa Minnillo and Nick Lachey. Tiger King also covers infamous rivalry with animal conservationist Carole Baskin and how Exotic hired hitman Allen Glover to murder her. The docuseries focuses on Joe Exotic’s life before he was imprisoned for killing tigers at his exotic animal park. The Netflix series is called Tiger King: Murder, Mayhem, and Madness went viral within a few days of its premiere on the streaming platform. Tiger King is a docuseries that follows the life of former Zoo owner Joe Maldonado a.k.a. These pictures are proof: All about Tiger King, Too Hot to Handle & Love is Blind Netflix series Reportedly, they are planning some project together and they all happen to now be in the same friend circle. Recently the contestants Damian, Francesca, and Harry from these shows were seen hanging out together with the Netflix series Tiger King star Dillon Passage. Both the shows have been receiving a lot of attention due to the format of the show as well as the reality TV angle of the web series. Anyone who is aware of the trending Netflix series would know that the OTT platform recently showcased two web series known as Too Hot To Handle as well as Love is Blind. 4/17/2023 0 Comments Stapled helixGiven these functional differences, MDM2 and MDMX are each unable to compensate for the loss of the other, and they regulate nonoverlapping functions of p53 ( 4, 6). MDMX does not have the intrinsic E3 ubiquitin ligase activity of MDM2 and cannot affect p53 stability, but MDM2/MDMX heterodimers can increase ubiquitin ligase activity relative to the MDM2 monomer. Amplification of MDMX is seen in many tumors, including melanoma, breast, head and neck, hepatocellular, and retinoblastoma, and, interestingly, amplification of MDMX appears to correlate with both p53WT status and an absence of MDM2 amplification ( 6, 9, 10). The other negative regulator, MDMX, possesses a similar p53-binding activity and also effectively inhibits p53 transcriptional activity. Consequently, aberrant MDM2 overexpression and gene amplification contribute to accelerated cancer development and growth ( 1, 8). MDM2 negatively regulates p53 function through multiple mechanisms, including direct binding that masks the p53 transactivation domain, impairing nuclear import of the p53 protein, and ubiquitination and proteasomal degradation of the p53 protein ( 6, 7). Cancers that overexpress the inhibitory proteins MDM2 and MDMX also possess wild-type p53 (p53WT), and thus pharmacological disruption of the interactions between p53 and MDM2 and MDMX offers the opportunity to restore p53-dependent cell-cycle arrest and apoptosis in this important class of tumors ( 3 – 6). Inactivation of this guardian of the genome either by deletion or mutation or through overexpression of inhibitory proteins is the most common defect in human cancers ( 1, 2). The human transcription factor protein p53 induces cell-cycle arrest and apoptosis in response to DNA damage and cellular stress and thereby plays a critical role in protecting cells from malignant transformation ( 1, 2). Overall, ATSP-7041 demonstrates in vitro and in vivo proof-of-concept that stapled peptides can be developed as therapeutically relevant inhibitors of protein–protein interaction and may offer a viable modality for cancer therapy. Most importantly, ATSP-7041 demonstrates robust p53-dependent tumor growth suppression in MDM2/MDMX-overexpressing xenograft cancer models, with a high correlation to on-target pharmacodynamic activity, and possesses favorable pharmacokinetic and tissue distribution properties. A high resolution (1.7-Å) X-ray crystal structure reveals its molecular interactions with the target protein MDMX, including multiple contacts with key amino acids as well as a role for the hydrocarbon staple itself in target engagement. Specifically, ATSP-7041 binds both MDM2 and MDMX with nanomolar affinities, shows submicromolar cellular activities in cancer cell lines in the presence of serum, and demonstrates highly specific, on-target mechanism of action. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX, ATSP-7041, which effectively activates the p53 pathway in tumors in vitro and in vivo. Okona first debuted on The Next Generation and was played by Billy Campbell, and the character was last seen on Lower Decks in a minor role but will return to Prodigy as a recurring character.Stapled α−helical peptides have emerged as a promising new modality for a wide range of therapeutic targets. Another way they may be trying to lure older fans into the series is with the series debut of another classic Star Trek character Thadiun Okona. It’s finding ways to appeal to both old and new fans alike. The show also brought in Spock, Odo, Uhura, and others for a special cameo as holodeck characters. The show has already used Kathryn Janeway (Kate Mulgrew) and Chakotay (Robert Beltran) to help attract fans of a different ages into the series, but that wasn’t all. It isn’t just trying to open up doors for new fans, however, as the series also does a great job of attracting older fans back with their use of classic characters. Star Trek: Prodigy is a great series that does a wonderful job of creating an entry point for new fans to get into the series. Star Trek: Prodigyg is returning on October 27 with a classic character in tow. |
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